Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 5/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326210 | 0.94 | ALDH1A1 (0.47) | KCNH2ADRB2ALDH1A1POLBOPRM1 | |
| SCHEMBL8323392 | 0.93 | KCNH2 (0.51) | KCNH2ALDH1A1POLBOPRM1KDM4E | |
| SCHEMBL8319818 | 0.87 | KDM4E (0.46) | KCNH2ALDH1A1TOP2ATOP2BKDM4E | |
| SCHEMBL8324813 | 0.86 | KCNH2 (0.53) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL8923183 | 0.85 | KCNH2 (0.43) | KCNH2ADRB2ALDH1A1POLBOPRM1 | |
| SCHEMBL8923177 | 0.84 | KCNH2 (0.51) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL8324816 | 0.82 | KCNH2 (0.42) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL8326222 | 0.82 | KCNH2 (0.43) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL8319673 | 0.82 | KCNH2 (0.61) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| Hydrochloric Acid SCHEMBL9154708 | 0.80 | ALDH1A1 (0.59) | KCNH2ADRB2ALDH1A1POLBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| US-5679689-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |