Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.68 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.68 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.68 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.68 |
| ▸ | HTR1A | P08908 | 4/20 | 0.66 |
| ▸ | DRD2 | P14416 | 4/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.57 |
| ▸ | MAOB | P27338 | 5/20 | 0.56 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8318929 | 0.98 | PTGER1 (0.67) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL9057460 | 0.91 | HTR1A (0.79) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL13940131 | 0.85 | PTGER1 (0.68) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8674682 | 0.84 | HTR1A (0.65) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL17197391 | 0.84 | HTR1A (0.79) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| Hydrochloric Acid SCHEMBL8677134 | 0.83 | HTR1A (0.63) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL2989204 | 0.83 | HTR1A (0.77) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8323719 | 0.82 | PTGER1 (0.81) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8326278 | 0.82 | PTGER4 (0.68) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8039309 | 0.81 | HTR1A (0.56) | PTGER1PTGER4PTGER3PTGER2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733033-B1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LTD (GB) | 1999-12-22 | — | — | EP | disclosed |
| EP-0733033-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-09-25 | — | — | EP | disclosed |
| WO-1996011902-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-04-25 | — | — | WO | disclosed |