Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | TLR4 | O00206 | 1/20 | 0.53 |
| ▸ | CPB1 | P15086 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 4/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326426 | 0.92 | ALDH1A1 (0.69) | ALDH1A1GAATSHREPHX1TLR4 | |
| SCHEMBL10325767 | 0.92 | ALDH1A1 (0.69) | ALDH1A1GAATSHREPHX1TLR4 | |
| SCHEMBL16055815 | 0.92 | ALDH1A1 (0.69) | ALDH1A1GAATSHREPHX1TLR4 | |
| SCHEMBL17506913 | 0.84 | ALDH1A1 (0.56) | ALDH1A1GAATSHREPHX1TLR4 | |
| SCHEMBL16324617 | 0.84 | ALDH1A1 (0.53) | ALDH1A1GAATSHREPHX1TLR4 | |
| SCHEMBL16323609 | 0.84 | ALDH1A1 (0.53) | ALDH1A1GAATSHREPHX1TLR4 | |
| SCHEMBL381922 | 0.83 | ALDH1A1 (0.85) | ALDH1A1GAATSHREPHX1TLR4 | |
| SCHEMBL3948456 | 0.83 | ALDH1A1 (0.85) | ALDH1A1GAATSHREPHX1TLR4 | |
| SCHEMBL3948461 | 0.83 | ALDH1A1 (0.85) | ALDH1A1GAATSHREPHX1TLR4 | |
| SCHEMBL23539273 | 0.83 | ALDH1A1 (0.56) | ALDH1A1GAATSHREPHX1TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925624-A | ANTIINFLAMMATORY AGENTS TREATING PATIENTS WITH INFLAMMATORY CONDITIONS SUSCEPTIBLE TO LEUKOCYTE-INDUCED TISSUE DAMAGE | GLAXO GROUP LIMITED (GB) | 1999-07-20 | — | — | US | disclosed |
| US-5889178-A | N-(2,2-DIPHENYLETHYL)-DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-03-30 | — | — | US | disclosed |