Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 17/20 | 0.44 |
| ▸ | BRD2 | P25440 | 2/20 | 0.39 |
| ▸ | SMCHD1 | A6NHR9 | 1/20 | 0.39 |
| ▸ | MYO1G | B0I1T2 | 1/20 | 0.39 |
| ▸ | AIP | O00170 | 1/20 | 0.39 |
| ▸ | AP3B1 | O00203 | 1/20 | 0.39 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | SAP18 | O00422 | 1/20 | 0.39 |
| ▸ | KPNA3 | O00505 | 1/20 | 0.39 |
| ▸ | PPP6C | O00743 | 1/20 | 0.39 |
| ▸ | TCERG1 | O14776 | 1/20 | 0.39 |
| ▸ | UBE2L6 | O14933 | 1/20 | 0.39 |
| ▸ | PPP1R12A | O14974 | 1/20 | 0.39 |
| ▸ | U2SURP | O15042 | 1/20 | 0.39 |
| ▸ | SETD1A | O15047 | 1/20 | 0.39 |
| ▸ | ARPC1B | O15143 | 1/20 | 0.39 |
| ▸ | POLR1C | O15160 | 1/20 | 0.39 |
| ▸ | OGT | O15294 | 1/20 | 0.39 |
| ▸ | PPM1G | O15355 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318078 | 0.91 | BRD4 (0.44) | BRD4BRD2LMNABRD3MEN1 | |
| SCHEMBL8320603 | 0.88 | BRD4 (0.48) | BRD4BRD2LMNAHDAC1BRD3 | |
| SCHEMBL8322223 | 0.86 | BRD4 (0.40) | BRD4MEN1KMT2A | |
| SCHEMBL8318824 | 0.85 | BRD4 (0.45) | BRD4BRD2LMNAHDAC1BRD3 | |
| SCHEMBL21847182 | 0.83 | BRD4 (0.41) | BRD4BRD2SMCHD1MYO1GAIP | |
| SCHEMBL8318050 | 0.83 | BRD4 (0.63) | BRD4BRD2SMCHD1MYO1GAIP | |
| SCHEMBL8317706 | 0.82 | BRD4 (0.52) | BRD4BRD2LMNAHDAC1BRD3 | |
| SCHEMBL8319389 | 0.81 | BRD4 (0.46) | BRD4BRD2SMCHD1MYO1GAIP | |
| SCHEMBL8319404 | 0.81 | BRD4 (0.47) | BRD4BRD2BRD3NPC1RAB9A | |
| SCHEMBL21847192 | 0.81 | BRD4 (0.39) | BRD4BRD2SMCHD1MYO1GAIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934940-A1 | CYTOKINE PRODUCTION INHIBITORS, TRIAZEPINE COMPOUNDS, AND INTERMEDIATES THEREOF | Japan Tobacco Inc. (JP) | 1999-08-11 | — | — | EP | claimed |
| EP-0934940-A1 | CYTOKINE PRODUCTION INHIBITORS, TRIAZEPINE COMPOUNDS, AND INTERMEDIATES THEREOF | Japan Tobacco Inc. (JP) | 1999-08-11 | — | — | EP | disclosed |