Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320460 | 1.00 | CTSL (0.69) | CTSLATMMETTL3CTSBGAA | |
| SCHEMBL2675573 | 0.86 | CTSL (0.73) | CTSLATMMETTL3CTSBGAA | |
| SCHEMBL27647421 | 0.85 | CTSL (0.71) | CTSLATMMETTL3CTSBGAA | |
| SCHEMBL2674247 | 0.83 | CTSL (0.69) | CTSLATMMETTL3CTSBGAA | |
| SCHEMBL27627084 | 0.83 | CTSL (0.69) | CTSLATMMETTL3CTSBMAPT | |
| SCHEMBL27647321 | 0.83 | CTSL (0.69) | CTSLATMMETTL3CTSBGAA | |
| SCHEMBL7167509 | 0.82 | CTSL (0.68) | CTSLATMMETTL3CTSBGAA | |
| SCHEMBL7167512 | 0.82 | CTSL (0.68) | CTSLATMMETTL3CTSBGAA | |
| SCHEMBL27999578 | 0.81 | CTSL (0.70) | CTSLATMMETTL3CTSBGAA | |
| SCHEMBL8426262 | 0.81 | CTSL (0.66) | CTSLATMMETTL3CTSBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977170-A | HIGH DENISTY LIPOPROTEINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-02 | — | — | US | claimed |
| WO-1998057927-A1 | ELEVATION OF HDL CHOLESTEROL BY 4-[(AMINOTHIOXOMETHYL)HYDRAZONO]-4-ARYLBUTYL CARBAMATES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-12-23 | — | — | WO | claimed |