Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | PPOX | P50336 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.38 |
| ▸ | THRB | P10828 | 5/20 | 0.38 |
| ▸ | THRA | P10827 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321859 | 0.91 | MEN1 (0.46) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL8325245 | 0.89 | HDAC3 (0.39) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL9751312 | 0.89 | MEN1 (0.41) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL11865317 | 0.83 | MEN1 (0.49) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL9751497 | 0.82 | TDP1 (0.58) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL9751346 | 0.81 | MEN1 (0.48) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL9796491 | 0.81 | MEN1 (0.58) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL10482278 | 0.80 | TLR8 (0.36) | TLR8TLR7THRBTHRA | |
| SCHEMBL11856491 | 0.80 | NOTUM (0.43) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL10803315 | 0.78 | TLR7 (0.42) | TLR8TLR7THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883282-A | UREA CHEMICAL INTERMEDIATES; RICE | AMERICAN CYANAMID COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| US-5763605-A | 3-(3-aryloxyphenyl)-1-(substituted methyl)-S-triazine-2,4,6-oxo or thiotrione herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-06-09 | — | — | US | disclosed |
| US-5670641-A | 3-(3-aryloxyphenyl)-1-(substituted methyl)-S-triazine-2,4,6-oxo or thiotrione herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1997-09-23 | — | — | US | disclosed |
| US-5654256-A | PREEMERGENCE, POSTEMERGENCE HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1997-08-05 | — | — | US | disclosed |
| US-5604180-A | RICE CROPS | AMERICAN CYANAMID COMPANY | 1997-02-18 | — | — | US | disclosed |
| EP-0745595-A1 | 3-(3-Aryloxyphenyl)-1-(substituted methyl)-s-triazine-2,4,6-oxo or thiotrione herbicidal agents | American Cyanamid Company (US) | 1996-12-04 | — | — | EP | disclosed |
| US-5519133-A | CYCLIZATION, ALKYLATION | AMERICAN CYANAMID CO. (US) | 1996-05-21 | — | — | US | disclosed |