Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | PPOX | P50336 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751305 | 0.95 | MEN1 (0.47) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL10667115 | 0.92 | MEN1 (0.52) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL9751312 | 0.90 | MEN1 (0.41) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL8321859 | 0.89 | MEN1 (0.46) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL10809942 | 0.85 | RAF1 (0.45) | TLR8ALDH1A1TLR7 | |
| SCHEMBL9751309 | 0.85 | TDP1 (0.70) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL8382590 | 0.84 | MEN1 (0.47) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL9751482 | 0.83 | TLR7 (0.41) | TLR8TLR7 | |
| SCHEMBL10670395 | 0.82 | SCN9A (0.53) | — | |
| SCHEMBL8320672 | 0.81 | MEN1 (0.39) | MEN1TTRPPOXKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992089-A | Pre- and postemergence | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-12 | — | — | US | disclosed |
| EP-0228788-B1 | HERBICIDAL DERIVATIVES OF SUBSTITUTED BENZOYL-HYDRAZINIUM COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-12-27 | — | — | EP | disclosed |
| US-4778914-A | FOR HALOGENATED DIPHENYL ETHER HERBICIDE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-10-18 | — | — | US | disclosed |
| EP-0122037-B1 | SUBSTITUTED DIPHENYLETHER COMPOUNDS USEFUL AS HERBICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-08-19 | — | — | EP | disclosed |
| EP-0228788-A1 | Herbicidal derivatives of substituted benzoyl-hydrazinium compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-15 | — | — | EP | disclosed |
| EP-0122037-A1 | Substituted diphenylether compounds useful as herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-10-17 | — | — | EP | disclosed |
| EP-0034402-B1 | METHOD OF PREPARING FLUORINE-SUBSTITUTED DIPHENYL ETHER DERIVATIVES AND FLUORINE-SUBSTITUTED HALOGENO BENZENE DERIVATIVES FOR USE THEREIN | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-08-29 | — | — | EP | disclosed |
| US-4388472-A | Substituted diphenyl ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-06-14 | — | — | US | disclosed |
| US-4384135-A | REACTING A SUBSTITUTED BENZOTRIFLUORIDE WITH A SUBSTITUTED PHENOL | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1983-05-17 | — | — | US | disclosed |
| EP-0023100-B1 | HERBICIDAL COMPOSITIONS COMPRISING A DIPHENYL ETHER COMPOUND IN ADMIXTURE WITH ANOTHER HERBICIDE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-11-10 | — | — | EP | disclosed |
| EP-0034402-A2 | Method of preparing fluorine-substituted diphenyl ether derivatives and fluorine-substituted halogeno benzene derivatives for use therein | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-08-26 | — | — | EP | disclosed |
| EP-0023100-A1 | Herbicidal compositions comprising a diphenyl ether compound in admixture with another herbicide | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-01-28 | — | — | EP | disclosed |