Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 5/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | PPOX | P50336 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11858023 | 0.89 | CFTR (0.45) | NOTUMKMT2AMAPTATMCFTR | |
| SCHEMBL11865317 | 0.86 | MEN1 (0.49) | KMT2ATHRBMRGPRX4THRATDP1 | |
| SCHEMBL11848309 | 0.86 | TDP1 (0.55) | KMT2AMAPTATMCFTRMRGPRX4 | |
| SCHEMBL11126204 | 0.83 | THRB (0.44) | KMT2ATHRBTHRATDP1MEN1 | |
| SCHEMBL8321859 | 0.80 | MEN1 (0.46) | KMT2ATHRBMRGPRX4THRATDP1 | |
| SCHEMBL8320672 | 0.80 | MEN1 (0.39) | KMT2ATHRBTHRATDP1MEN1 | |
| SCHEMBL8325245 | 0.79 | HDAC3 (0.39) | KMT2ATHRBTHRATDP1MEN1 | |
| SCHEMBL11854888 | 0.78 | NPBWR1 (0.41) | KMT2AMAPTTHRBTHRAMEN1 | |
| SCHEMBL11440623 | 0.78 | THRB (0.46) | THRBTHRANPBWR1MCHR1 | |
| SCHEMBL11854926 | 0.78 | HAO1 (0.40) | KMT2ATHRBTHRAMEN1NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957852-A | HERBICIDES | ISHIHARA SANGYO KAISHA LTD. (JA) | 1976-05-18 | — | — | US | claimed |
| US-3957852-A | HERBICIDES | ISHIHARA SANGYO KAISHA LTD. (JA) | 1976-05-18 | — | — | US | disclosed |