Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8316995 | 0.99 | SLC22A1 (0.50) | SLC22A1OPRM1OPRD1OPRK1SLC6A4 | |
| SCHEMBL8320764 | 0.96 | SLC22A1 (0.50) | SLC22A1OPRM1OPRD1OPRK1SLC6A4 | |
| Hydrochloric Acid SCHEMBL8319705 | 0.92 | SLC22A1 (0.52) | SLC22A1OPRM1OPRD1OPRK1SLC6A4 | |
| Hydrochloric Acid SCHEMBL8317914 | 0.89 | OPRM1 (0.46) | SLC22A1OPRM1OPRD1OPRK1SLC6A4 | |
| SCHEMBL29204727 | 0.86 | SLC22A1 (0.54) | SLC22A1OPRM1OPRD1OPRK1SLC6A4 | |
| SCHEMBL27499030 | 0.80 | SLC22A1 (0.47) | SLC22A1OPRM1OPRD1OPRK1SLC6A4 | |
| Hydrochloric Acid SCHEMBL8319682 | 0.78 | SLC22A1 (0.50) | SLC22A1OPRM1OPRD1OPRK1SLC6A4 | |
| Hydrochloric Acid SCHEMBL8318722 | 0.76 | OPRM1 (0.48) | SLC22A1OPRM1OPRD1OPRK1SLC6A4 | |
| SCHEMBL4813929 | 0.76 | SLC22A1 (0.50) | SLC22A1OPRM1OPRD1OPRK1SLC6A4 | |
| SCHEMBL28438723 | 0.75 | SLC22A1 (0.42) | SLC22A1OPRM1OPRD1OPRK1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923536-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1999-06-23 | — | — | EP | claimed |
| WO-1998004517-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-02-05 | — | — | WO | claimed |
| EP-0923536-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998004517-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-02-05 | — | — | WO | disclosed |