Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | TOP1 | P11387 | 5/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320856 | 1.00 | KDM4E (0.55) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL8476554 | 0.88 | CHRM2 (0.60) | KDM4EHSD17B10ALDH1A1HPGDCHRM2 | |
| SCHEMBL8324721 | 0.88 | CHRM2 (0.60) | KDM4EHSD17B10ALDH1A1HPGDCHRM2 | |
| SCHEMBL8318631 | 0.86 | KDM4E (0.52) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL8318633 | 0.86 | KDM4E (0.52) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL8324880 | 0.83 | ALDH1A1 (0.58) | KDM4EHSD17B10ALDH1A1HPGDCHRM2 | |
| SCHEMBL8473329 | 0.83 | ALDH1A1 (0.58) | KDM4EHSD17B10ALDH1A1HPGDCHRM2 | |
| SCHEMBL8323571 | 0.82 | KCNH2 (0.65) | KDM4EHSD17B10ALDH1A1HPGDCHRM2 | |
| SCHEMBL8323573 | 0.82 | KCNH2 (0.65) | KDM4EHSD17B10ALDH1A1HPGDCHRM2 | |
| SCHEMBL10686208 | 0.79 | KDM4E (0.66) | KDM4EHSD17B10ALDH1A1HPGDPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962468-A | ANTIBACTERIAL ACTIVITY | LG CHEMICAL LTD. (KR) | 1999-10-05 | — | — | US | disclosed |
| EP-0688772-B1 | Quinoline carboxylic acid derivatives having 7-(4-amino-methyl-3-oxime) pyrrolidine substituents and processes for their preparation | LG CHEMICAL LTD (KR) | 1999-05-06 | — | — | EP | disclosed |
| US-5869670-A | BACTERICIDES | LG CHEMICAL LTD. (KR) | 1999-02-09 | — | — | US | disclosed |
| US-5840916-A | INTERMEDIATE FOR QUINOLONE ANTIBIOTICS; 4-AMINOMETHYL-3-METHOXYIMINOPYRROLIDINE | LG CHEMICAL LTD. (KR) | 1998-11-24 | — | — | US | disclosed |
| US-5776944-A | 7-(4-aminomethyl-3-methyloxyiminopyrroplidin-1-yl)-1-cyclopropyl-6-flu oro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid and the process for the preparation thereof | LG CHEMICAL LTD. (KR) | 1998-07-07 | — | — | US | disclosed |
| US-5698570-A | QUINOLONE ANTIBIOTIC; BACTERICIDES | LG CHEMICAL LTD. (KR) | 1997-12-16 | — | — | US | disclosed |
| US-5633262-A | BACTERICIDES | LG CHEMICAL LTD. (KR) | 1997-05-27 | — | — | US | disclosed |
| EP-0688772-A1 | Novel quinoline carboxylic acid derivatives having 7-(4-amino-methyl-3-oxime) pyrrolidine substituents and processes for their preparation | LG Chemical Limited (KR) | 1995-12-27 | — | — | EP | disclosed |