Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324910 | 0.84 | NQO2 (0.47) | GAATDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL4944488 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HPGDPTPN11 | |
| SCHEMBL8322998 | 0.81 | PRSS1 (0.52) | SMPD1HPGDKDM4ERAB9A | |
| SCHEMBL3431544 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HPGDPTPN11 | |
| SCHEMBL4946388 | 0.79 | ALDH1A1 (0.60) | ALDH1A1HPGDPTPN11 | |
| SCHEMBL8322921 | 0.79 | CYP1A2 (0.48) | TDP1L3MBTL1ALDH1A1HPGDRAB9A | |
| SCHEMBL3431580 | 0.78 | ALDH1A1 (0.63) | ALDH1A1HPGDPTPN11 | |
| SCHEMBL4943889 | 0.78 | ALDH1A1 (0.63) | ALDH1A1HPGDPTPN11 | |
| SCHEMBL3850273 | 0.77 | ERN1 (0.47) | ERN1 | |
| SCHEMBL3850277 | 0.77 | ERN1 (0.47) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073638-A2 | METHOD OF LOWERING BODY TEMPERATURE WITH (S)-2,3-BENZODIAZEPINES | VELA PHARMACEUTICALS, INC. (US) | 2004-09-02 | — | — | WO | disclosed |