Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.55 |
| ▸ | RARB | P10826 | 3/20 | 0.52 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.52 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3431544 | 0.97 | ALDH1A1 (0.54) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL4946388 | 0.97 | ALDH1A1 (0.60) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL3431580 | 0.95 | ALDH1A1 (0.63) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL4943889 | 0.95 | ALDH1A1 (0.63) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL4945100 | 0.92 | KMT2A (0.53) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL21828892 | 0.88 | TSHR (0.62) | TSHR | |
| SCHEMBL8322921 | 0.84 | CYP1A2 (0.48) | ALDH1A1HPGDTSHR | |
| SCHEMBL4023882 | 0.84 | POLB (0.64) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL8320882 | 0.82 | GAA (0.42) | ALDH1A1HPGDPTPN11 | |
| SCHEMBL17931010 | 0.81 | WDR5 (0.63) | ALDH1A1HPGDTP53TSHRPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1589136-A | Pharmaceutical and cosmetic compositions containing aromatic aldehydes bearing oxygen-containing groups | CUTANIX CORP (US) | 2005-03-02 | — | — | CN | claimed |
| US-20030124157-A1 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. | 2003-07-03 | — | — | US | claimed |
| US-10702515-B2 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. (US) | 2020-07-07 | — | — | US | disclosed |
| US-20180169086-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | ALLERGAN, INC. | 2018-06-21 | — | — | US | disclosed |
| US-9895361-B2 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. (US) | 2018-02-20 | — | — | US | disclosed |
| US-20160184289-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | ALLERGAN, INC. | 2016-06-30 | — | — | US | disclosed |
| US-9107874-B2 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. (US) | 2015-08-18 | — | — | US | disclosed |
| US-8496951-B2 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. (US) | 2013-07-30 | — | — | US | disclosed |
| CN-102973417-A | Pharmaceutical and cosmetic compositions containing oxy group-bearing aromatic aldehydes | CUTANIX CORP | 2013-03-20 | — | — | CN | disclosed |
| US-20130035359-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | ALLERGAN, INC. | 2013-02-07 | — | — | US | disclosed |
| US-8268336-B2 | Compositions containing aromatic aldehydes and their use in treatments | SKINMEDICA, INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-8246969-B2 | Use in cosmetics and as topical, transdermal or systemic antiinflammatory pharmaceuticals | SKINMEDICA, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| US-8246971-B2 | Compositions containing aromatic aldehydes and their use in treatment | SKINMEDICA, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| US-20120190753-A1 | Compositions Containing Aromatic Aldehydes and Their Use in Treatments | MERZ AESTHETICS, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120157546-A1 | Compositions Containing Aromatic Aldehydes and Their Use in Treatments | MERZ AESTHETICS, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20080004354-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENT | CUTANIX CORPORATION | 2008-01-03 | — | — | US | disclosed |
| CN-1589136-A | Pharmaceutical and cosmetic compositions containing aromatic aldehydes bearing oxygen-containing groups | CUTANIX CORP (US) | 2005-03-02 | — | — | CN | disclosed |
| US-20030124157-A1 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10702515-B2 | Compositions containing aromatic aldehydes and their use in treatments | TYR, ALDH2, AOX1 | ALDH1A1 4/4885HPGD 286/4885TP53 823/4885 |
| US-20180169086-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | TYR, ALDH2, AOX1 | ALDH1A1 4/4885HPGD 286/4885TP53 823/4885 |
| US-20120190753-A1 | Compositions Containing Aromatic Aldehydes and Their Use in Treatments | TYR, ALDH2, AOX1 | ALDH1A1 4/4885HPGD 286/4885TP53 823/4885 |
| US-20130035359-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | TYR, ALDH2, AOX1 | ALDH1A1 4/4885HPGD 286/4885TP53 823/4885 |
| US-20120157546-A1 | Compositions Containing Aromatic Aldehydes and Their Use in Treatments | TYR, ALDH2, AOX1 | ALDH1A1 4/4885HPGD 286/4885TP53 823/4885 |
| US-20030124157-A1 | Compositions containing aromatic aldehydes and their use in treatments | TYR, ALDH2, AOX1 | ALDH1A1 4/4885HPGD 286/4885TP53 823/4885 |
| US-20080004354-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENT | TYR, ALDH2, AOX1 | ALDH1A1 4/4885HPGD 272/4885TP53 943/4885 |
| US-20160184289-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | TYR, ALDH2, AOX1 | ALDH1A1 4/4885HPGD 286/4885TP53 823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.