Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1594378 | 0.98 | LMNA (0.52) | LMNAHTTALDH1A1KDM4EGAA | |
| Hydrochloric Acid SCHEMBL29102678 | 0.95 | LMNA (0.50) | LMNAHTTALDH1A1KDM4EGAA | |
| SCHEMBL15754742 | 0.87 | LMNA (0.44) | LMNAHTTALDH1A1KDM4EGAA | |
| SCHEMBL23566413 | 0.77 | LMNA (0.56) | LMNAHTTALDH1A1KDM4EGAA | |
| SCHEMBL513746 | 0.76 | EPHX2 (0.43) | LMNAHTTALDH1A1KDM4EGAA | |
| SCHEMBL27367787 | 0.76 | LMNA (0.66) | LMNAHTTALDH1A1KDM4EGAA | |
| SCHEMBL29287494 | 0.76 | EPHX2 (0.47) | LMNAHTTALDH1A1KDM4EGAA | |
| SCHEMBL4303429 | 0.75 | LMNA (0.54) | LMNAHTTALDH1A1KDM4EGAA | |
| SCHEMBL10960560 | 0.74 | KDM4E (0.48) | LMNAHTTKDM4ECYP1A2NPC1 | |
| SCHEMBL30449190 | 0.74 | ALDH1A1 (0.48) | LMNAALDH1A1GAACYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916660-A2 | Process for the production of sulphonylurea salts | Novartis AG (CH) | 1999-05-19 | — | — | EP | disclosed |