Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327663 | 0.87 | ROCK1 (0.44) | L3MBTL1TDP1POLBAPEX1YAP1 | |
| SCHEMBL23754645 | 0.84 | ALDH1A1 (0.45) | LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL25176172 | 0.83 | SLC2A1 (0.52) | LMNAL3MBTL1TDP1ALDH1A1MAPT | |
| SCHEMBL25419439 | 0.81 | LSS (0.38) | LMNAPOLBALDH1A1MAPTROCK1 | |
| SCHEMBL8328142 | 0.80 | HDAC1 (0.47) | GAALMNAL3MBTL1TDP1POLB | |
| SCHEMBL8325252 | 0.78 | HDAC1 (0.46) | GAALMNAL3MBTL1TDP1POLB | |
| SCHEMBL7609127 | 0.78 | ALDH1A1 (0.50) | L3MBTL1TDP1POLBAPEX1YAP1 | |
| SCHEMBL11527013 | 0.76 | TSHR (0.48) | ALDH1A1MAPT | |
| SCHEMBL23403744 | 0.73 | RAF1 (0.53) | — | |
| SCHEMBL3885094 | 0.73 | LMNA (0.51) | LMNAL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |