Thiophanate

Thiophanate

SCHEMBL8322113

CCOC(=O)NC(=S)Nc1ccccc1NC(=S)NC(=O)OCC.c1ccc2[nH]cnc2c1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.49
ATM Q13315 1/20 0.49
ALDH1A1 P00352 5/20 0.49
LMNA P02545 3/20 0.49
HPGD P15428 1/20 0.49
ALOX15 P16050 1/20 0.49
HSD17B10 Q99714 1/20 0.49
POLB P06746 5/20 0.47
MAPT P10636 3/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
GAA P10253 3/20 0.42
KDM4E B2RXH2 3/20 0.41
QPCT Q16769 1/20 0.41
GLA P06280 1/20 0.41
RXFP1 Q9HBX9 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiophanate SCHEMBL29398343 0.83 ALDH1A1 (0.70) ALDH1A1LMNAHPGDALOX15HSD17B10
Thiophanate SCHEMBL20842 0.83 ALDH1A1 (0.70) ALDH1A1LMNAHPGDALOX15HSD17B10
Thiophanate SCHEMBL7449541 0.81 ALDH1A1 (0.68) ALDH1A1LMNAHPGDALOX15HSD17B10
Thiophanate SCHEMBL10922494 0.79 ALDH1A1 (0.79) KMT2AALDH1A1LMNAHPGDALOX15
SCHEMBL12336304 0.79 ALDH1A1 (0.64) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL11694452 0.79 ALDH1A1 (0.79) KMT2AALDH1A1LMNAHPGDALOX15
SCHEMBL11835690 0.78 ALDH1A1 (0.62) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL11834021 0.78 ALDH1A1 (0.71) KMT2AALDH1A1LMNAHPGDALOX15
SCHEMBL11793473 0.78 ALDH1A1 (0.62) KMT2AALDH1A1LMNAHPGDALOX15
SCHEMBL11837150 0.78 ALDH1A1 (0.62) ALDH1A1LMNAHPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 933 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110294755-A Organic electroluminescent compounds and its application 北京诚志永华显示科技有限公司 2019-10-01 CN claimed
CN-110240547-A Organic compound and its preparing the application in organic electroluminescent device 北京诚志永华显示科技有限公司 2019-09-17 CN claimed
CN-110229071-A Fluorene derivative organic electroluminescence device 北京诚志永华显示科技有限公司 2019-09-13 CN claimed
CN-110041159-A New compound, electroluminescent organic material, organic electroluminescent device, electronic device 北京诚志永华显示科技有限公司 2019-07-23 CN claimed
CN-110003090-A Indene derivative, the organic electroluminescence device containing indene derivative 北京诚志永华显示科技有限公司 2019-07-12 CN claimed
CN-109970716-A Organic compound and its application in Organnic electroluminescent device 北京诚志永华显示科技有限公司 2019-07-05 CN claimed
CN-109912610-A Organic compound and its preparing the application in organic electroluminescent device 北京诚志永华显示科技有限公司 2019-06-21 CN claimed
CN-109912433-A New compound, electroluminescent organic material, organic electroluminescence device, electronic device 北京诚志永华显示科技有限公司 2019-06-21 CN claimed
CN-109686870-A Isotope composition, electroluminescent organic material, organic electroluminescence device, electronic equipment 北京诚志永华显示科技有限公司 2019-04-26 CN claimed
CN-105493303-B Polymeric organic semiconductor compositions 斯马特凯姆有限公司 2019-02-22 CN claimed
CN-1133173-A Preparation of diuretic by using neuropsychic tension antagonist SANOFI SA (FR) 1996-10-16 CN claimed
CN-1097192-A Retroviral protease inhibitors AMERICAN CYANAMID CO (US) 1995-01-11 CN claimed
US-4940722-A 1-/2,4-DICHLOROPHENYL/-4,4-DIMETHYL-2-/1,2,4-TRIAZOL-1-YL/--1 -PENTEN-3-OL, BENZIMIDAZOLE THIOPHANATE FUNGICIDE SUMITOMO CHEMICAL COMPANMY, LIMITED (JP) 1990-07-10 US claimed
EP-0274839-A1 A seed disinfectant composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-07-20 EP claimed
US-4608385-A EFFECTIVE AGAINST RESISTANT STRAINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-08-26 US claimed
EP-0078663-B1 FUNGICIDAL N-PHENYLCARBAMATES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-04-17 EP claimed
US-4482546-A Fungicidal N-phenylcarbamates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-11-13 US claimed
EP-0078663-A2 Fungicidal N-phenylcarbamates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-05-11 EP claimed
EP-0063905-A1 Fungicidal N-phenylcarbamates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-11-03 EP claimed
EP-0051871-A1 N-Phenylcarbamate derivatives, process for their preparation, fungicidal compositions and a method for controlling fungi SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-05-19 EP claimed