Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321153 | 0.91 | CYP1A2 (0.50) | MAPTUSP2SMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL8319119 | 0.85 | NR4A2 (0.38) | MAPTUSP2SMN1; SMN2TSHRLMNA | |
| SCHEMBL8320986 | 0.84 | MAPT (0.46) | MAPTUSP2SMN1; SMN2TSHRLMNA | |
| SCHEMBL8321684 | 0.80 | MEN1 (0.43) | MAPTSMN1; SMN2TSHRCYP1A2CYP2C19 | |
| SCHEMBL4042141 | 0.78 | MAPT (0.49) | MAPTUSP2SMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL4046879 | 0.77 | ALDH1A1 (0.48) | MAPTUSP2SMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL7566334 | 0.77 | MAPT (0.53) | MAPTTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8318820 | 0.76 | NR4A2 (0.40) | MAPTSMN1; SMN2TSHRLMNAKMT2A | |
| SCHEMBL1986500 | 0.76 | LMNA (0.48) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL23000249 | 0.75 | MAPT (0.49) | MAPTUSP2SMN1; SMN2TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10017548-A | — | — | None | — | — | JP | disclosed |
| US-5866594-A | Indole-2-carboxylate derivatives and fungicidal compositions for agricultural or horticultural use containing the derivatives as active component | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1999-02-02 | — | — | US | disclosed |
| JP-H1017548-A | INDOLE-2-CARBOXYLIC ESTER DERIVATIVE AND AGRICULTURAL/ HORTICULTURAL GERMICIDE WITH THE SAME AS ACTIVE INGREDIENT | OTSUKA CHEM CO LTD | 1998-01-20 | — | — | JP | disclosed |
| EP-0791582-A1 | INDOLE-2-CARBOXYLIC ESTER DERIVATIVES AND AGRICULTURAL AND HORTICULTURAL BACTERIOCIDES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-08-27 | — | — | EP | disclosed |