Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322195 | 1.00 | FUCA1 (0.56) | FUCA1GRIN2BHRH2ADRA1BOPRK1 | |
| SCHEMBL28716809 | 0.76 | GRIN2B (0.55) | FUCA1GRIN2BBCHEACHEBACE1 | |
| SCHEMBL14001426 | 0.76 | LTA4H (0.58) | FUCA1GRIN2BKDM1AMAOAHPGD | |
| SCHEMBL15818134 | 0.76 | LTA4H (0.58) | FUCA1GRIN2BALDH1A1BCHEACHE | |
| SCHEMBL9791812 | 0.76 | LTA4H (0.58) | FUCA1GRIN2BALDH1A1BCHEACHE | |
| SCHEMBL697761 | 0.76 | LTA4H (0.58) | FUCA1GRIN2BKDM1AMAOAHPGD | |
| SCHEMBL15780394 | 0.76 | LTA4H (0.58) | FUCA1GRIN2BKDM1AMAOAHPGD | |
| SCHEMBL13634413 | 0.76 | LTA4H (0.58) | FUCA1GRIN2BALDH1A1BCHEACHE | |
| SCHEMBL1847853 | 0.76 | LTA4H (0.58) | FUCA1GRIN2BALDH1A1BCHEACHE | |
| SCHEMBL15921601 | 0.76 | LTA4H (0.58) | FUCA1GRIN2BKDM1AMAOAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925624-A | ANTIINFLAMMATORY AGENTS TREATING PATIENTS WITH INFLAMMATORY CONDITIONS SUSCEPTIBLE TO LEUKOCYTE-INDUCED TISSUE DAMAGE | GLAXO GROUP LIMITED (GB) | 1999-07-20 | — | — | US | disclosed |
| US-5889178-A | N-(2,2-DIPHENYLETHYL)-DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-03-30 | — | — | US | disclosed |
| EP-0680488-B1 | 2,6-DIAMINOPURINE DERIVATIVES | GLAXO GROUP LTD (GB) | 1998-04-08 | — | — | EP | disclosed |