SCHEMBL8322304

SCHEMBL8322304

Cc1ccc(N(c2ccccc2)c2cccc3c(N(c4ccccc4)c4ccc(C)c(C)c4)cccc23)cc1C

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.40
CYP1A2 P05177 4/20 0.35
MAPT P10636 2/20 0.34
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
SIGMAR1 Q99720 2/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
POLB P06746 2/20 0.32
APP P05067 1/20 0.32
GAA P10253 1/20 0.32
CYP2A6 P11509 2/20 0.31
KDM1A O60341 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18978244 0.88 S1PR1 (0.36) S1PR1CYP1A2MAPTALDH1A1KDM4E
SCHEMBL22246993 0.87 S1PR1 (0.35) S1PR1CYP1A2GAA
SCHEMBL7764813 0.86 CYP2A6 (0.44) CYP1A2ALDH1A1SIGMAR1CYP2A6
SCHEMBL10053538 0.84 ALDH1A1 (0.42) CYP1A2MAPTALDH1A1CYP3A4TDP1
SCHEMBL10065973 0.83 ALDH1A1 (0.45) S1PR1CYP1A2MAPTALDH1A1KDM4E
SCHEMBL14163838 0.83 ALDH1A1 (0.48) S1PR1CYP1A2MAPTALDH1A1KDM4E
SCHEMBL295453 0.83 ALDH1A1 (0.48) S1PR1CYP1A2MAPTALDH1A1KDM4E
SCHEMBL26280939 0.83 ALDH1A1 (0.48) S1PR1CYP1A2MAPTALDH1A1KDM4E
SCHEMBL2310644 0.83 ALDH1A1 (0.48) S1PR1CYP1A2MAPTALDH1A1KDM4E
SCHEMBL1376567 0.82 CYP1A2 (0.38) S1PR1CYP1A2MAPTALDH1A1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699654-B1 Hole-transporting material and use thereof TOYO INK MFG CO (JP) 1999-03-31 EP disclosed
US-5681664-A CONTAINING A POLYAMINE TOYO INK MANUFACTURING CO., LTD. (JP) 1997-10-28 US disclosed
EP-0699654-A1 Hole-transporting material TOYO INK MANUFACTURING CO., LTD. (JP) 1996-03-06 EP disclosed