Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053538 | 0.91 | ALDH1A1 (0.42) | CYP2A6ALDH1A1SIGMAR1CYP1A2TSHR | |
| SCHEMBL12856349 | 0.87 | ALDH1A1 (0.44) | CYP2A6ALDH1A1SIGMAR1CYP1A2TSHR | |
| SCHEMBL8322304 | 0.86 | S1PR1 (0.40) | CYP2A6ALDH1A1SIGMAR1CYP1A2 | |
| SCHEMBL15014298 | 0.85 | CYP2A6 (0.42) | CYP2A6ALDH1A1SIGMAR1CYP1A2TSHR | |
| SCHEMBL2722078 | 0.84 | SIGMAR1 (0.42) | CYP2A6ALDH1A1SIGMAR1CYP1A2TSHR | |
| SCHEMBL29378684 | 0.84 | SIGMAR1 (0.42) | CYP2A6ALDH1A1SIGMAR1CYP1A2TSHR | |
| SCHEMBL22246993 | 0.83 | S1PR1 (0.35) | CYP1A2 | |
| SCHEMBL23513194 | 0.83 | SIGMAR1 (0.41) | CYP2A6ALDH1A1SIGMAR1CYP1A2TSHR | |
| SCHEMBL16638997 | 0.82 | CYP1A2 (0.42) | CYP2A6ALDH1A1SIGMAR1CYP1A2TSHR | |
| SCHEMBL18204288 | 0.82 | SIGMAR1 (0.40) | CYP2A6ALDH1A1SIGMAR1CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617005-B1 | Triarylamine compound, process for producing the same and electrophotographic photoreceptor using the same | FUJI XEROX CO LTD (JP) | 2001-06-13 | — | — | EP | disclosed |
| US-5587263-A | STABLE CHARGE TRANSPORT LAYER | FUJI XEROX CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5495049-A | CHARGE TRANSFER COMPOUNDS | FUJI XEROX CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0617005-A2 | Triarylamine compound, process for producing the same and electrophotographic photoreceptor using the same | FUJI XEROX CO., LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |