Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 14/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323776 | 0.93 | MEN1 (0.44) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8322083 | 0.91 | MEN1 (0.37) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8322412 | 0.87 | CACNA1F (0.62) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8324816 | 0.85 | KCNH2 (0.42) | KCNH2POLBMEN1KMT2ATOP2A | |
| SCHEMBL8321401 | 0.84 | GSK3B (0.38) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8323408 | 0.83 | KDM4E (0.35) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8319677 | 0.83 | KCNH2 (0.49) | KCNH2POLBMEN1KMT2ATOP2A | |
| SCHEMBL8319062 | 0.81 | KCNH2 (0.51) | KCNH2POLBGSK3BMEN1KMT2A | |
| SCHEMBL8324778 | 0.81 | ALDH1A1 (0.50) | KCNH2POLBMEN1KMT2ATOP2A | |
| SCHEMBL8317924 | 0.81 | ALDH1A1 (0.50) | KCNH2POLBMEN1KMT2ATOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |