Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321401 | 0.86 | GSK3B (0.38) | KDM4ECACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8323919 | 0.85 | KDM4E (0.50) | KDM4EPOLBKCNH2 | |
| SCHEMBL8322415 | 0.83 | KCNH2 (0.47) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9235745 | 0.82 | KDM4E (0.46) | KDM4ECACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9232358 | 0.81 | KDM4E (0.40) | KDM4ECACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9234627 | 0.81 | CACNA1F (0.51) | KDM4ECACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9233837 | 0.80 | KDM4E (0.54) | KDM4ECACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9228918 | 0.80 | KDM4E (0.40) | KDM4ECACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9232505 | 0.80 | KDM4E (0.44) | KDM4ECACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8131419 | 0.79 | CACNA1F (0.34) | KDM4ECACNA1FPOLBMAPK1CACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |