Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323758 | 0.90 | KDM4E (0.45) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL8925001 | 0.88 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL8925004 | 0.88 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL8925008 | 0.86 | KDM4E (0.36) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL8323426 | 0.85 | CYP3A4 (0.34) | ALDH1A1KDM4EHPGDHSD17B10TOP2A | |
| SCHEMBL8323544 | 0.85 | KDM4E (0.47) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL8321532 | 0.85 | ALDH1A1 (0.34) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL8321538 | 0.84 | EPHA2 (0.39) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL8320645 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CYP2C9CYP3A4 | |
| SCHEMBL8318803 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |