Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323542 | 0.89 | DRD3 (0.58) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL8921114 | 0.88 | DRD3 (0.57) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL8324379 | 0.87 | ALDH1A1 (0.35) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL8321532 | 0.87 | ALDH1A1 (0.34) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL8921121 | 0.86 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL8323758 | 0.86 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL8321538 | 0.85 | EPHA2 (0.39) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL8322831 | 0.85 | ALDH1A1 (0.35) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL9667763 | 0.81 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL8134972 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |