Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 4/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28914412 | 0.85 | CPB1 (0.58) | CPB1ALDH1A1GAACTSKCTSB | |
| SCHEMBL28914414 | 0.85 | CPB1 (0.58) | CPB1ALDH1A1GAACTSKCTSB | |
| SCHEMBL20749075 | 0.85 | CPB1 (0.58) | CPB1ALDH1A1GAACTSKCTSB | |
| SCHEMBL19630135 | 0.85 | CPB1 (0.58) | CPB1ALDH1A1GAACTSKCTSB | |
| SCHEMBL16683507 | 0.84 | CPB1 (0.47) | CPB1ALDH1A1GAACTSKCTSB | |
| SCHEMBL2851278 | 0.82 | CPB1 (0.46) | CPB1ALDH1A1GAACTSKCTSB | |
| SCHEMBL26632432 | 0.82 | CPB1 (0.46) | CPB1ALDH1A1GAACTSKCASP3 | |
| SCHEMBL2851275 | 0.82 | CPB1 (0.46) | CPB1ALDH1A1GAACTSKCTSB | |
| SCHEMBL2843716 | 0.81 | CPB1 (0.52) | CPB1ALDH1A1GAACTSKCTSB | |
| SCHEMBL4374791 | 0.81 | CPB1 (0.46) | CPB1ALDH1A1GAACTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925624-A | ANTIINFLAMMATORY AGENTS TREATING PATIENTS WITH INFLAMMATORY CONDITIONS SUSCEPTIBLE TO LEUKOCYTE-INDUCED TISSUE DAMAGE | GLAXO GROUP LIMITED (GB) | 1999-07-20 | — | — | US | disclosed |
| US-5889178-A | N-(2,2-DIPHENYLETHYL)-DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-03-30 | — | — | US | disclosed |