SCHEMBL20749075

SCHEMBL20749075

CO[C@H]1CCC[C@@H]1NC(=O)OCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CPB1 P15086 2/20 0.58
ALDH1A1 P00352 3/20 0.55
KDM4E B2RXH2 1/20 0.55
MAPT P10636 1/20 0.55
GAA P10253 1/20 0.53
CTSB P07858 2/20 0.52
CTSS P25774 2/20 0.52
CTSK P43235 2/20 0.52
TSHR P16473 1/20 0.51
EPHX1 P07099 1/20 0.51
CASP3 P42574 3/20 0.51
CTSL P07711 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19630135 1.00 CPB1 (0.58) CPB1ALDH1A1KDM4EMAPTGAA
SCHEMBL28914412 1.00 CPB1 (0.58) CPB1ALDH1A1KDM4EMAPTGAA
SCHEMBL28914414 1.00 CPB1 (0.58) CPB1ALDH1A1KDM4EMAPTGAA
SCHEMBL4574419 0.86 CPB1 (0.63) CPB1ALDH1A1GAACTSBCTSK
SCHEMBL8322874 0.85 CPB1 (0.51) CPB1ALDH1A1GAACTSBCTSS
SCHEMBL2843716 0.85 CPB1 (0.52) CPB1ALDH1A1GAACTSBCTSS
SCHEMBL6612597 0.84 EPHX1 (0.63) CPB1ALDH1A1GAACTSBCTSS
SCHEMBL22585843 0.84 CPB1 (0.57) CPB1ALDH1A1MAPTGAACTSB
SCHEMBL3563506 0.84 CPB1 (0.57) CPB1ALDH1A1GAACTSBCTSS
SCHEMBL19086685 0.84 CASP3 (0.53) CPB1ALDH1A1GAACTSBCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667631-B2 FGFR4 inhibitor, preparation method therefor, and applications thereof JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) 2023-06-06 US disclosed
EP-3444250-A1 FGFR4 INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) 2019-02-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667631-B2 FGFR4 inhibitor, preparation method therefor, and applications thereof FGFR4, FGFR1, FGFR2 CPB1 3117/4885ALDH1A1 855/4885KDM4E 1217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.