Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 9/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 9/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22223262 | 0.84 | GNAI3 (0.54) | GNAI3GNAI1GNAO1ITGB3ITGA2B | |
| SCHEMBL26038975 | 0.81 | GNAI3 (0.66) | GNAI3GNAI1GNAO1ITGB3ITGA2B | |
| SCHEMBL26038984 | 0.80 | GNAI3 (0.68) | GNAI3GNAI1GNAO1ITGB3ITGA2B | |
| SCHEMBL25499339 | 0.78 | GNAI3 (0.51) | GNAI3GNAI1GNAO1ITGB3ITGA2B | |
| SCHEMBL25500677 | 0.77 | GNAI3 (0.50) | GNAI3GNAI1GNAO1ITGB3ITGA2B | |
| SCHEMBL25499340 | 0.77 | GNAI3 (0.50) | GNAI3GNAI1GNAO1ITGB3ITGA2B | |
| SCHEMBL26038977 | 0.77 | GNAI3 (0.50) | GNAI3GNAI1GNAO1ITGB3ITGA2B | |
| SCHEMBL17739583 | 0.75 | GNAI3 (0.51) | GNAI3GNAI1GNAO1ITGB3ITGA2B | |
| Ammonia Solution, Strong SCHEMBL3990591 | 0.74 | GNAI3 (0.55) | GNAI3GNAI1GNAO1ITGB3ITGA2B | |
| SCHEMBL5242757 | 0.74 | ITGB3 (0.54) | GNAI3GNAI1GNAO1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058686-A1 | HYDROXYPROPYL AMIDES FOR THE TREATMENT OF ALZHEIMER’S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2004-07-15 | — | — | WO | disclosed |