Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.66 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.66 |
| ▸ | BCKDK | O14874 | 2/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.65 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13819863 | 0.85 | MCL1 (0.70) | MCL1BCL2L1BCKDKRXFP1TBXAS1 | |
| SCHEMBL2431312 | 0.83 | MAPT (0.52) | MCL1BCL2L1BCKDKRXFP1TBXAS1 | |
| SCHEMBL31207832 | 0.82 | TBXAS1 (0.58) | MCL1BCL2L1BCKDKRXFP1TBXAS1 | |
| SCHEMBL8020988 | 0.81 | CYP4F2 (0.54) | MCL1BCL2L1BCKDKRXFP1MAPT | |
| SCHEMBL417349 | 0.80 | MCL1 (1.00) | MCL1BCL2L1BCKDKRXFP1TBXAS1 | |
| SCHEMBL18050231 | 0.80 | MCL1 (0.71) | MCL1BCL2L1BCKDKRXFP1TBXAS1 | |
| SCHEMBL6886010 | 0.79 | MCL1 (1.00) | MCL1BCL2L1BCKDKRXFP1TBXAS1 | |
| Hydrochloric Acid SCHEMBL10855356 | 0.78 | MCL1 (0.69) | MCL1BCL2L1BCKDKRXFP1TBXAS1 | |
| Hydrochloric Acid SCHEMBL11398368 | 0.78 | MCL1 (0.97) | MCL1BCL2L1BCKDKRXFP1TBXAS1 | |
| Hydrochloric Acid SCHEMBL11394582 | 0.78 | MCL1 (0.97) | MCL1BCL2L1BCKDKRXFP1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921124-A1 | Benzothiophene derivatives useful in therapy | Pfizer Limited (GB) | 1999-06-09 | — | — | EP | disclosed |