Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.49 |
| ▸ | TUBB | P07437 | 7/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323706 | 0.89 | AADAT (0.49) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8324230 | 0.88 | KDM4E (0.49) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8326912 | 0.88 | AADAT (0.50) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8321401 | 0.86 | GSK3B (0.38) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8323919 | 0.85 | KDM4E (0.50) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL15090885 | 0.85 | AADAT (0.56) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8324816 | 0.83 | KCNH2 (0.42) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL8319677 | 0.83 | KCNH2 (0.49) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL15090826 | 0.83 | AADAT (0.54) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8323426 | 0.82 | CYP3A4 (0.34) | AADATKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |