Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326804 | 0.90 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL8326660 | 0.89 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL8326079 | 0.87 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL8323408 | 0.85 | KDM4E (0.35) | KDM4EPOLBKCNH2 | |
| SCHEMBL8323156 | 0.85 | AADAT (0.51) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL8324816 | 0.83 | KCNH2 (0.42) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL8319677 | 0.82 | KCNH2 (0.49) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL8136385 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL8319062 | 0.80 | KCNH2 (0.51) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL8317924 | 0.80 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |