Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.40 |
| ▸ | TUBB | P07437 | 4/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.40 |
| ▸ | PNP | P00491 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156547 | 0.77 | TUBB4A (0.45) | HAO1P4HBTUBB4ATUBBTUBA3C | |
| SCHEMBL8326813 | 0.75 | SMN1; SMN2 (0.42) | HAO1P4HBTUBB4ATUBBTUBA3C | |
| SCHEMBL7296430 | 0.73 | HTT (0.40) | MEN1KMT2APOLBMAPTIDO1 | |
| SCHEMBL8326815 | 0.73 | TSHR (0.39) | HAO1P4HBTUBB4ATUBBTUBA3C | |
| SCHEMBL7302854 | 0.70 | IDO1 (0.38) | PNPPOLBMAPTIDO1HPGD | |
| SCHEMBL9047855 | 0.70 | AR (0.47) | PNPPOLBSMN1; SMN2 | |
| Hydrogen Peroxide SCHEMBL28640288 | 0.68 | CA1 (0.55) | HAO1P4HBTUBB4ATUBBTUBA3C | |
| SCHEMBL4644640 | 0.68 | CA1 (0.60) | HAO1P4HBTUBB4ATUBBTUBA3C | |
| SCHEMBL31345525 | 0.68 | CA1 (0.60) | HAO1P4HBTUBB4ATUBBTUBA3C | |
| SCHEMBL9505741 | 0.66 | CA1 (0.57) | HAO1P4HBTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633259-B1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | HOFFMANN LA ROCHE (CH) | 1999-01-13 | — | — | EP | disclosed |
| US-5541186-A | ENDOTHELIN RECEPTOR INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0633259-A1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | F. HOFFMANN-LA ROCHE AG (CH) | 1995-01-11 | — | — | EP | disclosed |