SCHEMBL8323482

SCHEMBL8323482

CN(C)c1ccc(S(OS(C)(=O)=O)(c2ccc(OC(=O)OC(C)(C)C)cc2)c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.47
CA2 P00918 2/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA9 Q16790 1/20 0.37
KDM1A O60341 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MMP13 P45452 2/20 0.35
MMP8 P22894 4/20 0.34
MMP3 P08254 2/20 0.34
MAPT P10636 2/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
POLB P06746 1/20 0.34
PKM P14618 1/20 0.34
THRB P10828 1/20 0.34
GFER P55789 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8319947 1.00 ELANE (0.47) ELANECA2CA12CA1CA9
SCHEMBL8319678 0.91 ELANE (0.55) ELANECA2CA12CA1CA9
SCHEMBL8321680 0.89 ELANE (0.36) ELANECA2CA12CA9MEN1
SCHEMBL8325533 0.89 ELANE (0.36) ELANECA2CA12CA9MEN1
SCHEMBL8323469 0.86 ELANE (0.50) ELANECA2KDM1AMMP13MAPT
SCHEMBL8322611 0.82 PSEN1 (0.45) CA2CA12CA1CA9MEN1
SCHEMBL8324855 0.81 ALDH1A1 (0.38) CA2CA12CA1CA9KDM1A
SCHEMBL8318837 0.81 ALDH1A1 (0.38) CA2CA12CA1CA9KDM1A
SCHEMBL8319944 0.81 ELANE (0.48) ELANECA2CA12CA1CA9
SCHEMBL8323479 0.81 ELANE (0.48) ELANECA2CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5880169-A HAVING HIGH RESOLUTION FOR FINE PATTERNING SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-03-09 US disclosed