Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23570178 | 0.78 | SLC6A2 (0.45) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL15820188 | 0.77 | HSPB1 (0.80) | HSPB1ALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL5167786 | 0.73 | ALDH1A1 (0.71) | HSPB1ALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL4082910 | 0.73 | HSPB1 (0.68) | HSPB1ALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL31287841 | 0.73 | HSPB1 (0.82) | HSPB1ALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL22069631 | 0.73 | HSPB1 (0.57) | HSPB1ALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL27859313 | 0.72 | HSPB1 (0.82) | HSPB1ALDH1A1MAPTMAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL3143655 | 0.72 | KMT2A (0.69) | HSPB1ALDH1A1MAPTL3MBTL1TDP1 | |
| SCHEMBL22114132 | 0.72 | HSPB1 (0.63) | HSPB1ALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL1583899 | 0.72 | HSPB1 (0.63) | HSPB1ALDH1A1MAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039796-A1 | HETEROARYLOXY-SUBSTITUTED PHENYLAMINOPYRIMIDINES AS RHO-KINASE INHIBITORS | BAYER HEALTHCARE AG (DE) | 2004-05-13 | — | — | WO | disclosed |