Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 0.35 |
| ▸ | RXRG | P48443 | 17/20 | 0.35 |
| ▸ | RXRB | P28702 | 14/20 | 0.35 |
| ▸ | RARB | P10826 | 6/20 | 0.33 |
| ▸ | RARG | P13631 | 6/20 | 0.33 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309443 | 0.87 | RXRA (0.47) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL8309439 | 0.87 | RXRA (0.47) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL8323697 | 0.82 | RXRA (0.32) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL8323032 | 0.79 | RXRA (0.36) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL8320881 | 0.71 | RXRA (0.35) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7914094 | 0.68 | RXRA (0.52) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL6037058 | 0.68 | RXRA (0.52) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL6037060 | 0.63 | RXRA (0.53) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL6037059 | 0.63 | RXRA (0.53) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL22076589 | 0.61 | RXRA (0.73) | RXRARXRGRXRBRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800504-B1 | TRICYCLIC RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARM INC (US) | 1999-12-01 | — | — | EP | disclosed |