Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289110 | 0.88 | MCHR1 (0.42) | MCHR1 | |
| SCHEMBL14516861 | 0.87 | MCHR1 (0.42) | MCHR1PTGS2FFAR4 | |
| SCHEMBL221377 | 0.87 | PTGS2 (0.43) | PTGS1PTGS2 | |
| SCHEMBL29366997 | 0.87 | PTGS2 (0.43) | PTGS1PTGS2 | |
| SCHEMBL4197238 | 0.86 | PTGS2 (0.41) | PTGS1PTGS2 | |
| SCHEMBL4185476 | 0.86 | PTGS2 (0.34) | MCHR1PTGS2 | |
| SCHEMBL19953615 | 0.85 | PTGS2 (0.36) | PTGS1PTGS2 | |
| SCHEMBL17364528 | 0.85 | NPBWR1 (0.34) | MCHR1FFAR4 | |
| SCHEMBL2606110 | 0.83 | NPBWR1 (0.33) | MCHR1 | |
| SCHEMBL12052331 | 0.83 | MCHR1 (0.33) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060366-A1 | A METHOD FOR THE TREATMENT, PREVENTION, OR INHIBITION OF A CNS DISORDER AND/OR PAIN AND INFLAMMATION USING A COMBINATION OF DULOXETINE, VENLAFAXINE OR ATOMOXETINE AND A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND COMPOSITIONS THEREOF | PHARMACIA CORPORATION (US) | 2004-07-22 | — | — | WO | disclosed |