Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RRM1 | P23921 | 2/20 | 0.37 |
| ▸ | RRM2 | P31350 | 2/20 | 0.37 |
| ▸ | RRM2B | Q7LG56 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 3/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 3/20 | 0.33 |
| ▸ | CASP8 | Q14790 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GNPAT | O15228 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099887 | 0.80 | GRN (0.39) | RRM1RRM2RRM2BMMEGNPAT | |
| SCHEMBL5335559 | 0.80 | GRN (0.39) | RRM1RRM2RRM2BMMEGNPAT | |
| Hydrochloric Acid SCHEMBL7101089 | 0.78 | GRN (0.38) | RRM1RRM2RRM2BMMEGNPAT | |
| SCHEMBL14926782 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2CTSSCTSKALDH1A1POLB | |
| SCHEMBL14930543 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2CTSSCTSKALDH1A1POLB | |
| SCHEMBL29874685 | 0.77 | MME (0.40) | SMN1; SMN2MMECASP3CASP8CASP1 | |
| SCHEMBL8420112 | 0.77 | CASP3 (0.46) | CASP3CASP8CASP1CASP7 | |
| SCHEMBL759233 | 0.74 | MME (0.52) | MME | |
| SCHEMBL5691576 | 0.74 | MME (0.52) | MME | |
| SCHEMBL6904234 | 0.74 | MME (0.52) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0818463-B1 | Aspartyl dipeptide amide derivatives and sweeteners | AJINOMOTO KK (JP) | 1999-09-29 | — | — | EP | disclosed |
| US-5958496-A | LOW CALORIE SWEETENING FOR FOOD, BEVERAGES; TASTE, STABILITY | AJINOMOTO CO., INC. (JP) | 1999-09-28 | — | — | US | disclosed |
| EP-0818463-A1 | Aspartyl dipeptide amide derivatives and sweeteners | Ajinomoto Co., Ltd. (JP) | 1998-01-14 | — | — | EP | disclosed |