Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 14/20 | 0.46 |
| ▸ | CASP8 | Q14790 | 11/20 | 0.46 |
| ▸ | CASP1 | P29466 | 8/20 | 0.46 |
| ▸ | CASP7 | P55210 | 8/20 | 0.46 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | CASP4 | P49662 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323771 | 0.77 | RRM1 (0.37) | CASP3CASP8CASP1CASP7 | |
| SCHEMBL5691576 | 0.71 | MME (0.52) | MMP2MMP3 | |
| SCHEMBL759233 | 0.71 | MME (0.52) | MMP2MMP3 | |
| SCHEMBL6904234 | 0.71 | MME (0.52) | MMP2MMP3 | |
| SCHEMBL19952964 | 0.69 | MAPT (0.34) | CASP3CASP8MMP2MMP3 | |
| SCHEMBL27521568 | 0.69 | RIPK1 (0.41) | MMP2MMP3 | |
| SCHEMBL28868942 | 0.69 | RIPK1 (0.41) | MMP2MMP3 | |
| SCHEMBL4311 | 0.68 | ALDH1A1 (0.55) | — | |
| SCHEMBL12202138 | 0.68 | MME (0.41) | MMP2MMP3 | |
| SCHEMBL5053951 | 0.68 | ALDH1A1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0818463-B1 | Aspartyl dipeptide amide derivatives and sweeteners | AJINOMOTO KK (JP) | 1999-09-29 | — | — | EP | disclosed |
| EP-0818463-A1 | Aspartyl dipeptide amide derivatives and sweeteners | Ajinomoto Co., Ltd. (JP) | 1998-01-14 | — | — | EP | disclosed |