Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | ME2 | P23368 | 1/20 | 0.45 |
| ▸ | ME1 | P48163 | 1/20 | 0.45 |
| ▸ | ME3 | Q16798 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325276 | 0.88 | NPSR1 (0.51) | ABCB1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8661802 | 0.88 | NPSR1 (0.51) | ABCB1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL22911172 | 0.83 | MAPT (0.58) | MAPTLMNAALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL8664298 | 0.82 | MAPT (0.59) | MAPTLMNAALDH1A1SMN1; SMN2ITGB3 | |
| SCHEMBL8661753 | 0.82 | MAPT (0.59) | MAPTLMNAALDH1A1SMN1; SMN2ITGB3 | |
| SCHEMBL12814098 | 0.82 | NPSR1 (0.55) | MAPTLMNAALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL7369010 | 0.81 | MAPT (0.59) | MAPTLMNAALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL8663767 | 0.81 | MAPT (0.50) | MAPTLMNAALDH1A1SMN1; SMN2ITGB3 | |
| SCHEMBL24378197 | 0.81 | MAPT (0.61) | MAPTLMNAALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL5573222 | 0.79 | MAPT (0.76) | MAPTLMNAALDH1A1SMN1; SMN2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912175-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-09-08 | — | — | EP | disclosed |
| EP-0912175-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998000134-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1998-01-08 | — | — | WO | disclosed |