Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661802 | 1.00 | NPSR1 (0.51) | NPSR1ABCB1ATMMAPTLMNA | |
| SCHEMBL12814098 | 0.95 | NPSR1 (0.55) | NPSR1ATMMAPTLMNAALDH1A1 | |
| SCHEMBL8323807 | 0.88 | ABCB1 (0.52) | NPSR1ABCB1MAPTLMNAALDH1A1 | |
| SCHEMBL22911172 | 0.85 | MAPT (0.58) | NPSR1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7365804 | 0.84 | GPR119 (0.56) | NPSR1ATMGPR119 | |
| SCHEMBL7369010 | 0.83 | MAPT (0.59) | NPSR1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL24378197 | 0.83 | MAPT (0.61) | NPSR1MAPTLMNAALDH1A1GAA | |
| SCHEMBL7364473 | 0.83 | GPR119 (0.53) | ABCB1ATMMAPTLMNAALDH1A1 | |
| SCHEMBL4719112 | 0.83 | ABCB1 (0.56) | NPSR1ABCB1MAPTLMNAALDH1A1 | |
| SCHEMBL4719115 | 0.83 | ABCB1 (0.56) | NPSR1ABCB1MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912175-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-09-08 | — | — | EP | disclosed |
| EP-0912175-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1999-05-06 | — | — | EP | disclosed |
| US-5854245-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-29 | — | — | US | disclosed |
| WO-1998000134-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1998-01-08 | — | — | WO | disclosed |