Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.65 |
| ▸ | HPGD | P15428 | 5/20 | 0.65 |
| ▸ | LCK | P06239 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12879918 | 0.86 | RAB9A (0.55) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL8323799 | 0.85 | HSD17B3 (0.67) | KDM4EALDH1A1HPGDLCKPOLB | |
| SCHEMBL14473750 | 0.85 | KDM4E (0.76) | KDM4EALDH1A1HPGDLCKCYP2D6 | |
| SCHEMBL12879923 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1HPGDCYP2D6HSD17B10 | |
| SCHEMBL15984893 | 0.82 | KDM4E (0.71) | KDM4EALDH1A1HPGDLCKCYP2D6 | |
| SCHEMBL8321944 | 0.81 | KDM4E (0.62) | KDM4EALDH1A1HPGDLCKCYP2D6 | |
| SCHEMBL6439485 | 0.81 | KDM4E (0.69) | KDM4EALDH1A1HPGDLCKCYP2D6 | |
| SCHEMBL6031499 | 0.80 | CYP2D6 (0.76) | KDM4EALDH1A1HPGDLCKCYP2D6 | |
| SCHEMBL29975674 | 0.78 | CYP2D6 (0.68) | KDM4EALDH1A1HPGDLCKCYP2D6 | |
| SCHEMBL9797535 | 0.78 | CYP2D6 (0.68) | KDM4EALDH1A1HPGDLCKCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858652-A | USING A CAPTURE PRIMER CONJUGATED TO FIRST MEMBER OF BINDING PAIR AND A LABELED PRIMER; FOR AUTOMATED SEPARATION OF DOUBLE STRANDED EXTENSION PRODUCT USING SOLID PHASE CONJUGATED TO OTHER BINDING PAIR MEMBER | ABBOTT LABORATORIES (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0413152-B1 | 7-Hydroxy coumarins having substitutions in the 4 position | ABBOTT LAB (US) | 1996-01-10 | — | — | EP | disclosed |
| EP-0357011-B1 | Detection and amplification of target nucleic acid sequences | ABBOTT LAB (US) | 1994-08-31 | — | — | EP | disclosed |
| US-5247099-A | Process for synthesis of 7-hydroxy coumarins having substitutions in the 4-position | ABBOTT LABORATORIES (US) | 1993-09-21 | — | — | US | disclosed |
| US-5208350-A | Fluorescent dyes | ABBOTT LABORATORIES (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0413152-A1 | 7-Hydroxy coumarins having substitutions in the 4 position | ABBOTT LABORATORIES (US) | 1991-02-20 | — | — | EP | disclosed |
| EP-0357011-A2 | Detection and amplification of target nucleic acid sequences | ABBOTT LABORATORIES (US) | 1990-03-07 | — | — | EP | disclosed |