Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 9/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.65 |
| ▸ | GLA | P06280 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | CASP1 | P29466 | 2/20 | 0.65 |
| ▸ | CASP7 | P55210 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | FYN | P06241 | 1/20 | 0.56 |
| ▸ | GRB2 | P62993 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12879918 | 0.89 | RAB9A (0.55) | HSD17B3KDM4EALDH1A1GAAGLA | |
| SCHEMBL4209634 | 0.87 | KDM4E (0.76) | HSD17B3KDM4EALDH1A1GAAGLA | |
| SCHEMBL12879923 | 0.86 | KDM4E (0.51) | HSD17B3KDM4EALDH1A1GAAGLA | |
| SCHEMBL8324046 | 0.85 | KDM4E (0.65) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL2791708 | 0.81 | AKR1B1 (0.74) | HSD17B3KDM4EALDH1A1GAAGLA | |
| SCHEMBL536846 | 0.81 | HSD17B3 (1.00) | HSD17B3KDM4EALDH1A1GAAGLA | |
| SCHEMBL3762732 | 0.79 | HSD17B3 (1.00) | HSD17B3KDM4EALDH1A1GAAGLA | |
| SCHEMBL2554744 | 0.79 | KDM4E (1.00) | HSD17B3KDM4EALDH1A1GAAGLA | |
| SCHEMBL30406107 | 0.79 | KDM4E (1.00) | HSD17B3KDM4EALDH1A1GAAGLA | |
| SCHEMBL19767586 | 0.79 | ALDH1A1 (0.71) | HSD17B3KDM4EALDH1A1GAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858652-A | USING A CAPTURE PRIMER CONJUGATED TO FIRST MEMBER OF BINDING PAIR AND A LABELED PRIMER; FOR AUTOMATED SEPARATION OF DOUBLE STRANDED EXTENSION PRODUCT USING SOLID PHASE CONJUGATED TO OTHER BINDING PAIR MEMBER | ABBOTT LABORATORIES (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0413152-B1 | 7-Hydroxy coumarins having substitutions in the 4 position | ABBOTT LAB (US) | 1996-01-10 | — | — | EP | disclosed |
| EP-0357011-B1 | Detection and amplification of target nucleic acid sequences | ABBOTT LAB (US) | 1994-08-31 | — | — | EP | disclosed |
| US-5247099-A | Process for synthesis of 7-hydroxy coumarins having substitutions in the 4-position | ABBOTT LABORATORIES (US) | 1993-09-21 | — | — | US | disclosed |
| US-5208350-A | Fluorescent dyes | ABBOTT LABORATORIES (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0413152-A1 | 7-Hydroxy coumarins having substitutions in the 4 position | ABBOTT LABORATORIES (US) | 1991-02-20 | — | — | EP | disclosed |
| EP-0357011-A2 | Detection and amplification of target nucleic acid sequences | ABBOTT LABORATORIES (US) | 1990-03-07 | — | — | EP | disclosed |