Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CTSK | P43235 | 3/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.47 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.47 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.47 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.47 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544232 | 0.90 | KMT2A (0.69) | KMT2ACTSKCTSSADORA1HDAC8 | |
| SCHEMBL1357714 | 0.90 | KMT2A (0.69) | KMT2ACTSKCTSSADORA1HDAC8 | |
| SCHEMBL1357718 | 0.90 | KMT2A (0.69) | KMT2ACTSKCTSSADORA1HDAC8 | |
| SCHEMBL9543730 | 0.85 | CTSL (0.55) | KMT2ACTSKCTSSMEN1 | |
| SCHEMBL5444581 | 0.84 | CTSK (0.59) | KMT2ACTSKCTSSADORA1L3MBTL1 | |
| SCHEMBL9545318 | 0.84 | CTSK (0.54) | CTSKCTSSMAPTL3MBTL1MAPK1 | |
| SCHEMBL9545088 | 0.83 | CCKBR (0.54) | KMT2ACTSKCTSSMEN1 | |
| SCHEMBL28650975 | 0.82 | CTSK (0.56) | KMT2ACTSKDRD2MEN1MAPT | |
| SCHEMBL29758964 | 0.82 | CTSK (0.56) | KMT2ACTSKDRD2MEN1MAPT | |
| SCHEMBL18215088 | 0.82 | CTSK (0.56) | KMT2ACTSKDRD2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |