Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 13/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 3/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326800 | 0.87 | CYP19A1 (0.44) | CYP19A1NOS3NOS1NOS2GRM5 | |
| SCHEMBL8325621 | 0.86 | CYP19A1 (0.44) | CYP19A1NOS3NOS1NOS2CYP3A4 | |
| SCHEMBL8327043 | 0.86 | CYP19A1 (0.45) | CYP19A1CYP3A4VNN1STS | |
| SCHEMBL27282324 | 0.84 | EGLN2 (0.38) | CYP19A1NOS3NOS1NOS2CYP3A4 | |
| SCHEMBL8327987 | 0.80 | CYP19A1 (0.42) | CYP19A1VNN1STS | |
| SCHEMBL6063814 | 0.80 | CYP19A1 (0.38) | CYP19A1GRM5VNN1 | |
| SCHEMBL8328066 | 0.79 | CYP19A1 (0.44) | CYP19A1STS | |
| SCHEMBL30262487 | 0.79 | CYP19A1 (0.37) | CYP19A1NOS3NOS1NOS2CYP3A4 | |
| SCHEMBL28922397 | 0.79 | CYP19A1 (0.46) | CYP19A1STS | |
| SCHEMBL8323103 | 0.78 | ESR1 (0.49) | CYP19A1VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640595-B1 | SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-5538976-A | ANTICARCINOGENIC AGENTS AND ENZYME INHIBITORS FOR AROMATASE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0640595-A1 | NOVEL SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |
| CN-1079962-A | New substituted tertiary amine compound and salt thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1993-12-29 | — | — | CN | disclosed |