Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31453528 | 0.76 | SMN1; SMN2 (0.60) | SMN1; SMN2NSD2LSSRAB9ALMNA | |
| SCHEMBL11113968 | 0.71 | SMN1; SMN2 (0.47) | SMN1; SMN2NSD2LSSRAB9ALMNA | |
| SCHEMBL8328125 | 0.71 | SMN1; SMN2 (0.50) | SMN1; SMN2NSD2LSSRAB9AKMT2A | |
| SCHEMBL10385413 | 0.70 | SMN1; SMN2 (0.45) | SMN1; SMN2NSD2LSSRAB9ALMNA | |
| SCHEMBL28362457 | 0.67 | CYP1A2 (0.49) | NSD2LSSRAB9AKMT2ACYP1A2 | |
| SCHEMBL15282513 | 0.67 | PTPN1 (0.52) | SMN1; SMN2LSSRAB9ALMNAKMT2A | |
| SCHEMBL176438 | 0.66 | MEN1 (0.47) | SMN1; SMN2LMNAKMT2ATSHRMAPT | |
| SCHEMBL27721331 | 0.66 | KMT2A (0.40) | SMN1; SMN2LSSRAB9AKMT2ACYP1A2 | |
| SCHEMBL11782027 | 0.66 | TSHR (0.47) | SMN1; SMN2LSSLMNAKMT2ATSHR | |
| SCHEMBL3823752 | 0.66 | CES2 (0.53) | SMN1; SMN2LSSRAB9ALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |