Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | LSS | P48449 | 2/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31453528 | 0.86 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9AKMT2AMEN1LSS | |
| SCHEMBL176438 | 0.77 | MEN1 (0.47) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11114846 | 0.76 | MAOA (0.42) | SMN1; SMN2RAB9AKMT2AMEN1GPR55 | |
| SCHEMBL15453459 | 0.73 | MAOA (0.54) | RAB9AKMT2AMAOAMAOBLIMK2 | |
| SCHEMBL9657085 | 0.71 | ALDH5A1 (0.48) | SMN1; SMN2RAB9AKMT2AMEN1OPRD1 | |
| SCHEMBL30578615 | 0.71 | TSHR (0.46) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8324345 | 0.71 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9AKMT2ALSSNSD2 | |
| SCHEMBL8961259 | 0.70 | ALDH1A1 (0.42) | SMN1; SMN2RAB9AKMT2AMEN1GPR55 | |
| SCHEMBL9067824 | 0.69 | SMN1; SMN2 (0.49) | SMN1; SMN2KMT2AMEN1SLC6A2CES2 | |
| SCHEMBL31516874 | 0.69 | ALDH1A1 (0.51) | SMN1; SMN2KMT2AMEN1OPRD1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |