Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST6GAL1 | P15907 | 3/20 | 0.61 |
| ▸ | ST3GAL1 | Q11201 | 2/20 | 0.61 |
| ▸ | ST3GAL3 | Q11203 | 2/20 | 0.61 |
| ▸ | FUT6 | P51993 | 1/20 | 0.53 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.53 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13663950 | 0.61 | ALOX5 (0.38) | — | |
| SCHEMBL13663952 | 0.59 | ALOX5 (0.35) | — | |
| SCHEMBL22863220 | 0.58 | ALOX5 (0.37) | — | |
| SCHEMBL24632196 | 0.57 | ALOX5 (0.36) | — | |
| SCHEMBL23940968 | 0.57 | ALOX5 (0.33) | — | |
| SCHEMBL8147735 | 0.56 | ST6GAL1 (0.46) | ST6GAL1ST3GAL1ST3GAL3FUT6FUT5 | |
| SCHEMBL8147732 | 0.56 | ST6GAL1 (0.46) | ST6GAL1ST3GAL1ST3GAL3FUT6FUT5 | |
| SCHEMBL24827775 | 0.56 | ALOX5 (0.38) | — | |
| SCHEMBL7415930 | 0.55 | ALOX15 (0.69) | — | |
| SCHEMBL7415929 | 0.55 | ALOX15 (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572697-B1 | SPIROBENZOFURANLACTAM DERIVATIVES, METHODS FOR THEIR PREPARATION, AND USE THEREOF | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-02-21 | — | — | EP | disclosed |
| US-7160917-B2 | Spirobenzofuran lactams and their derivatives, processes for their preparation and use thereof | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-01-09 | — | — | US | disclosed |
| US-7160917-B2 | Spirobenzofuran lactams and their derivatives, processes for their preparation and use thereof | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-01-09 | — | — | US | disclosed |
| WO-2004055021-A1 | NOVEL SPIROBENZOFURANLACTAMS AND THE DERIVATIVES THEREOF, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-07-01 | — | — | WO | disclosed |