SCHEMBL8324521

SCHEMBL8324521

CCCCCCOc1cccc(-c2c(NC(=O)Nc3c(C(C)C)cccc3C(C)C)c(=O)n(CCCC)c3ncccc23)c1

nearest known ligand 0.85

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACAT1 P24752 1/20 0.80
SOAT1 P35610 1/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8327206 0.96 ACAT1 (0.81) ACAT1SOAT1
SCHEMBL8327975 0.95 ACAT1 (0.78) ACAT1SOAT1
SCHEMBL6639853 0.95 ACAT1 (0.85) ACAT1SOAT1
SCHEMBL6635258 0.95 ACAT1 (0.89) ACAT1SOAT1
SCHEMBL6634021 0.95 ACAT1 (0.79) ACAT1SOAT1
SCHEMBL6632704 0.94 ACAT1 (0.80) ACAT1SOAT1
SCHEMBL8325861 0.93 ACAT1 (0.77) ACAT1SOAT1
SCHEMBL6635954 0.93 ACAT1 (0.76) ACAT1SOAT1
SCHEMBL8331142 0.93 ACAT1 (0.76) ACAT1SOAT1
SCHEMBL6634517 0.93 ACAT1 (0.76) ACAT1SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0947515-A1 NOVEL NAPHTHYRIDINE DERIVATIVES SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1999-10-06 EP disclosed