Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.89 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.86 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6639853 | 0.98 | ACAT1 (0.85) | ACAT1SOAT1PDE4AKCNH2PDE4B | |
| SCHEMBL8327206 | 0.95 | ACAT1 (0.81) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL8324521 | 0.95 | ACAT1 (0.80) | ACAT1SOAT1 | |
| SCHEMBL2881680 | 0.94 | ACAT1 (1.00) | ACAT1SOAT1 | |
| SCHEMBL6634021 | 0.94 | ACAT1 (0.79) | ACAT1SOAT1PDE4AKCNH2PDE4B | |
| Hydrochloric Acid SCHEMBL5953470 | 0.94 | SOAT1 (0.99) | ACAT1SOAT1 | |
| SCHEMBL8327975 | 0.93 | ACAT1 (0.78) | ACAT1SOAT1PDE4AKCNH2PDE4B | |
| SCHEMBL6632704 | 0.93 | ACAT1 (0.80) | ACAT1SOAT1PDE4AKCNH2PDE4B | |
| Hydrochloric Acid SCHEMBL5953844 | 0.93 | SOAT1 (1.00) | ACAT1SOAT1 | |
| SCHEMBL8325861 | 0.93 | ACAT1 (0.77) | ACAT1SOAT1PDE4AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842933-B1 | NOVEL NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMA (JP) | 2004-08-04 | — | — | EP | disclosed |
| EP-0842933-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-05-20 | — | — | EP | disclosed |