Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324644 | 0.87 | PTPN1 (0.34) | PTPN1CA1BLMKDM1AKDM4C | |
| SCHEMBL10636366 | 0.81 | KDM4C (0.36) | PTPN1CA1BLMKDM4CKDM4A | |
| SCHEMBL5613242 | 0.76 | CA1 (0.48) | PTPN1CA1BLMKDM1AKDM4C | |
| SCHEMBL7614748 | 0.76 | KMT2A (0.47) | PTPN1 | |
| SCHEMBL4943247 | 0.75 | — | — | |
| SCHEMBL9164807 | 0.74 | KMT2A (0.50) | PTPN1 | |
| SCHEMBL7947728 | 0.74 | KMT2A (0.50) | PTPN1 | |
| SCHEMBL11716766 | 0.74 | KMT2A (0.50) | PTPN1 | |
| SCHEMBL2527461 | 0.72 | CA1 (0.44) | PTPN1CA1BLMKDM1AKDM4C | |
| SCHEMBL110410 | 0.72 | CA1 (0.50) | PTPN1CA1BLMKDM1AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886034-A | ANTIULCER AGENTS | KABUSHIKI KAISHA UENO SEIYAKU KENKYUJO (JP) | 1999-03-23 | — | — | US | disclosed |
| US-5380709-A | Prostaglandins E and anti ulcers containing same | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1995-01-10 | — | — | US | disclosed |
| US-5284858-A | Prostaglandins E and anti ulcers containing same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1994-02-08 | — | — | US | disclosed |
| US-5225439-A | Side effect reduction | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1993-07-06 | — | — | US | disclosed |
| US-5166174-A | For duodenal ulcers or gastric ulcers | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1992-11-24 | — | — | US | disclosed |
| EP-0284180-B1 | PROSTAGLANDINS E AND ANTI ULCERS CONTAINING SAME | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1992-08-19 | — | — | EP | disclosed |
| EP-0284180-A1 | Prostaglandins E and anti ulcers containing same | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1988-09-28 | — | — | EP | disclosed |