SCHEMBL8324644

SCHEMBL8324644

CC(C)CCCC(=O)CO[PH](=O)O

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.34
CA1 P00915 2/20 0.33
KDM1A O60341 1/20 0.33
BLM P54132 1/20 0.32
KDM4C Q9H3R0 2/20 0.30
KDM4A O75164 1/20 0.30
PHF8 Q9UPP1 1/20 0.30
KDM2A Q9Y2K7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10636366 0.95 KDM4C (0.36) PTPN1CA1BLMKDM4CKDM4A
SCHEMBL8324641 0.87 PTPN1 (0.35) PTPN1CA1KDM1ABLMKDM4C
SCHEMBL7614751 0.77 KMT2A (0.45) PTPN1
SCHEMBL4945889 0.76
SCHEMBL4943252 0.76
SCHEMBL9164814 0.76 KMT2A (0.48) PTPN1
SCHEMBL7947732 0.76 KMT2A (0.48) PTPN1
SCHEMBL11716770 0.76 KMT2A (0.48) PTPN1
SCHEMBL5613242 0.75 CA1 (0.48) PTPN1CA1KDM1ABLMKDM4C
SCHEMBL12610481 0.74 ALDH1A1 (0.33) CA1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5886034-A ANTIULCER AGENTS KABUSHIKI KAISHA UENO SEIYAKU KENKYUJO (JP) 1999-03-23 US disclosed
US-5380709-A Prostaglandins E and anti ulcers containing same K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1995-01-10 US disclosed
US-5284858-A Prostaglandins E and anti ulcers containing same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1994-02-08 US disclosed
US-5225439-A Side effect reduction K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1993-07-06 US disclosed
US-5166174-A For duodenal ulcers or gastric ulcers K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1992-11-24 US disclosed
EP-0284180-B1 PROSTAGLANDINS E AND ANTI ULCERS CONTAINING SAME Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-08-19 EP disclosed
EP-0284180-A1 Prostaglandins E and anti ulcers containing same Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1988-09-28 EP disclosed