Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.50 |
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
| ▸ | GLI1 | P08151 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.37 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.37 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749879 | 0.85 | SCN4A (0.46) | DPP4DPP9SCN4AGLI1PRCP | |
| SCHEMBL7749876 | 0.85 | SCN4A (0.46) | DPP4DPP9SCN4AGLI1PRCP | |
| SCHEMBL3330058 | 0.80 | SCN4A (0.49) | DPP4DPP9SCN4AGLI1PRCP | |
| SCHEMBL4579452 | 0.77 | SCN4A (0.47) | DPP4DPP9SCN4AGLI1PRCP | |
| SCHEMBL4579448 | 0.77 | SCN4A (0.47) | DPP4DPP9SCN4AGLI1PRCP | |
| SCHEMBL14537859 | 0.77 | SCN4A (0.47) | DPP4DPP9SCN4AGLI1PRCP | |
| SCHEMBL8788154 | 0.77 | SCN4A (0.47) | DPP4DPP9SCN4AGLI1PRCP | |
| SCHEMBL29772688 | 0.77 | SCN4A (0.47) | DPP4DPP9SCN4AGLI1PRCP | |
| SCHEMBL16557813 | 0.76 | DPP4 (0.37) | DPP4DPP9SCN4APRCPPFKFB2 | |
| SCHEMBL8294324 | 0.75 | DPP4 (0.50) | DPP4DPP9SCN4APRCPPFKFB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1553937-B1 | GLYCINENITRILE-BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | BRISTOL MYERS SQUIBB CO (US) | 2010-06-02 | — | — | EP | disclosed |
| WO-2004037181-A2 | GLYCINENITRILE-BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND METHODS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-05-06 | — | — | WO | disclosed |